Wednesday, October 21, 2015

Are you in pain? Please read this before taking an analgesic

By Paz Etcheverry, Ph.D.

We have known, for quite some time, that nonsteroidal anti-inflammatory medications (NSAIDs), commonly used to treat joint and muscle aches and pain, are not kind to our stomach cells. These drugs increase the risk of gastric ulcers and bleeding. These, my friends, are the mild effects. What is becoming more evident within the medical and scientific communities is that the ingestion of NSAIDs is associated with increased risk of cardiovascular events (e.g., heart attack and stroke), especially in patients who take them on a daily basis.

In case you are wondering, NSAIDs include

  • Aspirin (Aspirin is a brand name; the chemical is called acetylsalicylic acid)
  • Celecoxib (Celebrex)
  • Dexdetoprofen (Keral)
  • Diclofenac (Voltaren, Cataflam, Voltaren-XR)
  • Diflunisal (Dolobid)
  • Etodolac (Lodine, Lodine XL)
  • Etoricoxib (Algix)
  • Fenoprofen (Fenopron, Nalfron)
  • Firocoxib (Equioxx, Previcox)
  • Flurbiprofen (Urbifen, Ansaid, Flurwood, Froben)
  • Ibuprofen (Advil, Brufen, Motrin, Nurofen, Medipren, Nuprin)
  • Indomethacin (Indocin, Indocin SR, Indocin IV)
  • Ketoprofen (Actron, Orudis, Oruvail, Ketoflam)
  • Ketorolac (Toradol, Sprix, Toradol IV/IM, Toradol IM)
  • Licofelone (under development)
  • Lornoxicam (Xefo)
  • Loxoprofen (Loxonin, Loxomac, Oxeno)
  • Lumiracoxib (Prexige)
  • Meclofenamic acid (Meclomen)
  • Mefenamic acid (Ponstel)
  • Meloxicam (Movalis, Melox, Recoxa, Mobic)
  • Nabumetone (Relafen)
  • Naproxen (Aleve, Anaprox, Midol Extended Relief, Naprosyn, Naprelan)
  • Nimesulide (Sulide, Nimalox, Mesulid)
  • Oxaporozin (Daypro, Dayrun, Duraprox)
  • Parecoxib (Dynastat)
  • Piroxicam (Feldene)
  • Rofecoxib (Vioxx, Ceoxx, Ceeoxx)
  • Salsalate (Mono-Gesic, Salflex, Disalcid, Salsitab)
  • Sulindac (Clinoril)
  • Tenoxicam (Mobiflex)
  • Tolfenamic acid (Clotam Rapid, Tufnil)
  • Valdecoxib (Bextra)

Weight loss, mild physical activity, and anti-inflammatory diets rich in omega 3 fatty acids and low in omega 6 fatty acids may all be beneficial in the treatment of chronic joint and muscle pain. Additionally, topical treatments containing NSAIDs, e.g., gels, ointments, creams, and patches, may relieve pain without many of the adverse effects observed with pills. What about acetaminophen (Tylenol)? Acetaminophen, while not a member of the NSAID family, has its risks. The regular consumption of Tylenol increases the risk of liver damage.

Reference

NSAIDs List (n.d.) Retrieved from http://www.nsaids-list.com/

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